Introduction to Self-Service DNA-Encoded libraries (DELs)

DNA-Encoded library (DEL) screening is now commonly used in the pharmaceutical industry to find novel chemical matter that modulates protein targets of interest. We will discuss how DELopen and DELight kits work. DELopen is a freely accessible collection of DELs that can be used for academic drug-discovery. DELight is a self-service kit that allows pharmaceutical companies to conduct a DEL screen in their own lab, without needing to reveal the identity of their target.

Who should attend
  • Academics interested in screening their (protein/biomolecule) targets for drug-like chemical matter using freely accessible DELs.
  • Industry scientists interested in conducting DEL screens without revealing target identity and/or developing proprietary screening techniques in their own labs.
What will be learned
  • Basics of how the WuXi DEL-encoded library (DEL) platform works
  • Workflow and costs for academic labs to access DELopen
  • How a pharmaceutical company would use a DELight kit
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Alex Satz

Alex Satz

Senior Director DEL Strategy and Operations, WuXi AppTec

Alex Satz has 15+ years experience building DNA encoded library (DEL) platforms, and is currently the senior director of DEL strategy and operations at WuXi AppTec. Prior to WuXi AppTec, Alex led the Roche DEL platform in Basel Switzerland, and helped to develop the first industrial-scale DEL platform at Praecis Pharmaceuticals and GlaxoSmithKline.

Arsalan Arif

arsalan arif

Founder & Publisher, Endpoints News

Arsalan Arif is a news media entrepreneur who set out in 2015 to build his vision of an independent biotech news company at Endpoints News.